When the ER Gets It Wrong: Common Emergency Room Misdiagnoses

The emergency room is supposed to be where lives are saved — not where serious conditions get overlooked. But for all the life-or-death decisions happening behind those doors, the truth is uncomfortable: ERs misdiagnose more often than the public realizes. And when they do, the consequences can be deadly.

If you've ever left an ER visit thinking, “Something still doesn’t feel right,” — you’re not alone. You might have even been right.

The Numbers Tell a Grim Story

A 2022 report funded by the U.S. Department of Health and Human Services estimated that one in 18 emergency room patients is misdiagnosed — that’s about 7.4 million patients every year in the United States. Of those, 370,000 suffer serious harm, including permanent injury or death.

Let that sink in.

These are people showing up scared, vulnerable, and in pain — and instead of getting answers, they’re getting sent home with the wrong label, the wrong medication, or no treatment at all.

Five Conditions Emergency Rooms Frequently Miss

ER doctors are under pressure to move fast, make snap judgments, and trust that their instincts are right. But some conditions don’t scream their diagnosis — they whisper. These are the ones that get missed the most:

1. Stroke

Many strokes — especially in younger patients or women — present with vague symptoms: dizziness, nausea, fatigue. Doctors may dismiss them as migraines, anxiety, or even intoxication. Delay in diagnosis can mean irreversible brain damage or death.

2. Heart Attack (Especially in Women)

We’re taught that a heart attack means crushing chest pain. But for many — particularly women — it might feel like fatigue, indigestion, or back pain. ER doctors sometimes chalk these symptoms up to acid reflux or panic attacks.

3. Aortic Dissection

A tear in the wall of the aorta, this is a surgical emergency. It can present as “the worst chest pain of my life,” but also as back pain or even fainting. If missed, it’s often fatal within hours.

4. Sepsis

Sepsis is the body’s extreme response to infection. Its early signs can be subtle — fever, confusion, rapid heart rate. Too often it’s mistaken for the flu or a minor infection. Every hour of delay in treatment raises the risk of death.

5. Pulmonary Embolism

A blood clot in the lungs can mimic pneumonia, asthma, or simple shortness of breath. It’s common in patients who’ve recently had surgery, been immobile, or are taking birth control. If untreated, it can kill within minutes.

Why These Mistakes Happen

Emergency medicine is chaotic, yes — but that’s no excuse. Common causes of misdiagnosis include:
- Rushed evaluations
- Bias (“young people don’t have heart attacks”)
- Failure to listen to the patient’s full story
- Overreliance on incomplete tests
- Poor handoffs between staff during shift changes

In many of our cases, the signs were right there in the chart — but no one put the pieces together.

What You Can Do

If you're in the ER, or there with someone you care about, don’t be afraid to:
- Ask questions: “What else could this be?” “Could this be something more serious?”
- Repeat the key facts: Symptoms, timing, changes. Be clear and direct.
- Request further testing if symptoms are unexplained or severe
- Insist on documentation: Ask what diagnosis they’re entering, and what follow-up they recommend

And if you’ve already been discharged but something still feels wrong — trust your instincts and go back. It’s better to be safe than sorry.

When a Missed Diagnosis Crosses the Line

Not every missed diagnosis is malpractice. But when the ER fails to meet basic standards of care — when they ignore red flags, dismiss patient concerns, or cut corners on evaluation — and someone is seriously harmed or dies as a result, that’s not just unfortunate. That’s negligence.

If this happened to you or a loved one, you have the right to ask hard questions and get honest answers. And if the system won’t hold itself accountable, we will.